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hung k do[Author]
(1 results)?
Challenges in treating Pompe disease: an industry perspective.
Ann Transl Med. 2019 Jul;7(13):291. doi: 10.21037/atm.2019.04.15.
Ann Transl Med. 2019.
PMID: 31392203
Free PMC article.
Review.
Improved efficacy of a next-generation ERT in murine Pompe disease.
Xu S, Lun Y, Frascella M, Garcia A, Soska R, Nair A, Ponery AS, Schilling A, Feng J, Tuske S, Valle MCD, Martina JA, Ralston E, Gotschall R, Valenzano KJ, Puertollano R, Do HV, Raben N, Khanna R.
Xu S, et al. Among authors: do hv.
JCI Insight. 2019 Mar 7;4(5):e125358. doi: 10.1172/jci.insight.125358. eCollection 2019 Mar 7.
JCI Insight. 2019.
PMID: 30843882
Free PMC article.
Item in Clipboard
Endolysosomal N-glycan processing is critical to attain the most active form of the enzyme acid alpha-glucosidase.
Selvan N, Mehta N, Venkateswaran S, Brignol N, Graziano M, Sheikh MO, McAnany Y, Hung F, Madrid M, Krampetz R, Siano N, Mehta A, Brudvig J, Gotschall R, Weimer JM, Do HV.
Selvan N, et al. Among authors: do hv.
J Biol Chem. 2021 Jan-Jun;296:100769. doi: 10.1016/j.jbc.2021.100769. Epub 2021 May 8.
J Biol Chem. 2021.
PMID: 33971197
Free PMC article.
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The pharmacological chaperone AT2220 increases the specific activity and lysosomal delivery of mutant acid alpha-glucosidase, and promotes glycogen reduction in a transgenic mouse model of Pompe disease.
Khanna R, Powe AC Jr, Lun Y, Soska R, Feng J, Dhulipala R, Frascella M, Garcia A, Pellegrino LJ, Xu S, Brignol N, Toth MJ, Do HV, Lockhart DJ, Wustman BA, Valenzano KJ.
Khanna R, et al. Among authors: do hv.
PLoS One. 2014 Jul 18;9(7):e102092. doi: 10.1371/journal.pone.0102092. eCollection 2014.
PLoS One. 2014.
PMID: 25036864
Free PMC article.
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The pharmacological chaperone 1-deoxynojirimycin increases the activity and lysosomal trafficking of multiple mutant forms of acid alpha-glucosidase.
Flanagan JJ, Rossi B, Tang K, Wu X, Mascioli K, Donaudy F, Tuzzi MR, Fontana F, Cubellis MV, Porto C, Benjamin E, Lockhart DJ, Valenzano KJ, Andria G, Parenti G, Do HV.
Flanagan JJ, et al. Among authors: do hv.
Hum Mutat. 2009 Dec;30(12):1683-92. doi: 10.1002/humu.21121.
Hum Mutat. 2009.
PMID: 19862843
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